Connect with us

Society

Ministry approves clinical trial of new COVID-19 vaccine

Published

on

 

A resident in northern Lạng Sơn Province is vaccinated against COVID-19. The Ministry of Health has allowed VinBioCare to carry out clinical trial study of a new vacicne. — VNA/ Photo 

HÀ NỘI —  Vingroup’s affiliate VinBioCare has received approval for clinical trial from the Ministry of Health to advance ARCT-154, a new generation Arcturus vaccine targeting SARS-CoV-2 variants of concern, including the Delta variant.

VinBioCare had negotiated with Arcturus Therapeutics medicines biotechnology company of the US on the purchase and transfer of COVID-19 vaccine production technology.

The ARCT-154 clinical study is a randomised, observer-blind, placebo-controlled design, and is sponsored and completely funded by Arcturus’ manufacturing partner Vinbiocare.

The study will be carried out in Việt Nam in three phases on adult volunteers.

It aims to assess the safety, immunogenicity and efficacy of the SARS-CoV-2 self-amplifying mRNA vaccine, and will enrol up to 21,000 participants across the three phases, with 20,000 in Phase 3.

The first phase is scheduled to begin on August 8 by the Hanoi Medical University.

Primary endpoints include safety and efficacy with immunogenicity being evaluated in a subgroup. Participants will receive two doses of study vaccine separated by 28 days. Placebo participants will receive active vaccine after 6 months. All participants will be followed up for 1 year.

Joseph Payne, President and CEO of Arcturus, said: “We are very pleased to advance ARCT-154 into a significant, staged Phase 3 clinical development study with our partner to target SARS-CoV-2 variants of concern, including the Delta variant. ARCT-154 utilises Arcturus’ STARR™ mRNA technology, and our preclinical immunogenicity data demonstrates that our newly developed vaccine candidate elicits a strong neutralising antibody immune response against the Delta variant and other variants of concern.”

If the clinical trials prove successful at interim evaluations, Emergency Use Approval (EUA) by the Ministry of Health is anticipated in December 2021.

Technology transfer

Vingroup announced on Monday that it had signed an agreement with Arcturus Therapeutics on the transfer of COVID-19 vaccine production technology.

With a capacity to manufacture 200 million doses per year, Vingroup is projected to produce the first batches of vaccine by early 2022.

Arcturus Therapeutics is a leading clinical-stage messenger RNA medicines company focusing on the discovery, development and commercialisation of therapeutics for rare diseases and vaccines. 

Under the agreement, the US firm will grant permission for Vingroup’s affiliate VinBioCare to produce COVID-19 vaccine named VBC-COV19-154, which targets new variants of the coronavirus such as Delta and Alpha.

The Vietnamese company is also approved to manufacture other COVID-19 vaccine types of Arcturus such as ARCT-021.

The transfer is slated to begin this month.

VinBioCare’s plant will be located at the Hà Nội-based Hòa Lạc Hi-tech Park, which is built at an investment of over US$200 million.

Necessary devices will be flown to Việt Nam by September and the installation inside the plant is forecast to complete by two months later.

 

 

 

 

 

Source: https://vietnamnews.vn/society/1002911/ministry-approves-clinical-trial-of-new-covid-19-vaccine.html

Society

Over 67% of Covid-19 patients at HCM City Covid-19 Resuscitation Hospital need psychological support

Published

on

According to a survey by the Covid-19 Resuscitation Hospital in HCM City, up to 67% of patients said they wanted to have psychological counseling.

Hơn 67% F0 ở Bệnh viện Hồi sức Covid-19 muốn được hỗ trợ tâm lý
Psychologist Tri Thi Minh Thuy talks with a severe Covid-19 patient who has recovered from the disease and is about to be discharged from the hospital. Photo: Cho Ray Hospital.

According to the survey, 20% of the patients suffered depression, 53.3% with anxiety disorder, and 16.7% with stress.

In particular, up to 66.7% patients who needed High Flow Nasal Cannula (HFNC) suffered from depression. Similarly, 66.7% patients who had to breathe oxygen through a mask or mechanical ventilator suffered from anxiety disorder.

As many as 67% of patients wanted psychological counseling during treatment and after being discharged from the hospital.

The hospital has invited psychologist Tri Thi Minh Thuy from the University of Social Sciences and Humanities, Ho Chi Minh City, to survey and provide psychological treatment support for patients at the hospital.

“When they go to the hospital for Covid-19 treatment, patients have to be away from their families and fight the virus alone to survive so it’s easy to cause sadness and loss of appetite,” said Dr. Thuy.

“Seeing me, many patients remained still. I said if you agree to talk to me, please give me a sign. They understood what I was saying but did not do anything. I had to help them eat and drink, talk to them, give them a massage, then they began to open their hearts,” she said.

After getting into contact with many severely ill Covid-19 patients, Dr. Thuy concluded that they suffered from anxiety, panic attacks, or depression. This is why they need a psychologist.

Tu Anh

Source: https://vietnamnet.vn/en/society/over-67-of-covid-19-patients-at-hcm-city-covid-19-resuscitation-hospital-need-psychological-support-776618.html

Continue Reading

Society

Côn Đảo to return to ‘new normal’ under province’s proposal

Published

on

Bà Rịa – Vũng Tàu Province is drafting plans for reopening after September 22. — Photo courtesy of nld.com.vn

HCM CITY — Several wards and communes in Bà Rịa – Vũng Tàu Province are expected to continue to be under the Government’s Directive 16, while Côn Đảo District would return to a “new normal” state.

The provincial Steering Committee for COVID-19 Prevention and Control on Tuesday held a meeting on epidemic prevention and control plans after September 22 to discuss ending the province’s 5th social distancing period.

Directive 16 would continue to be applied in wards Nguyễn An Ninh, Thắng Nhất, Thắng Nhì, 1, 10 and 11, located in various districts.

Some communes and towns in Long Điền District, namely Phước Hưng, An Ngãi and Long Hải, will also be under Directive 16.

Bà Rịa City, Phú Mỹ Town, Châu Đức District, Đất Đỏ District and Xuyên Mộc District, together with the remaining communes and towns of Long Điền District, will be under the more relaxed Directive 15.

Production and business activities in Côn Đảo District will resume in a new normal state. However, traffic from the mainland to the island must be carefully monitored.

Districts such as Châu Đức, Đất Đỏ, Xuyên Mộc and Bà Rịa City aim to slowly recover and carefully open some types of economic activities in four stages.

During the first stage, between September 23 and 30, those areas will loosen travel control in the “green zone” and reopen supermarkets, retail store chains, small businesses selling essential items, traditional markets and take-away food services, and resume agricultural, forestry and fishery production activities.

The second stage, from October 1 to 31, involves tourism at hotels with closed services.

If the epidemic continues to be controlled well and Bà Rịa – Vũng Tàu returns to the new normal, the third stage, from November 11 to December 31, will be implemented.

The locality will allow tourist and resort establishments to welcome guests who are fully vaccinated. Real estate agencies, and security and insurance activities will be permitted to open, and intra-provincial public transport will operate at 50 per cent capacity. Education, training services and sports activities would be limited to no more than 20 people.

All economic activities in the last stage will reopen in 2022.

Vice chairman of the provincial People’s Committee Trần Văn Tuấn is seeking feedback from authorities and will announce the final plan soon.

As of September 21, after more than two months of social distancing, Bà Rịa – Vũng Tàu had recorded 3,943 COVID-19 cases. — 

Source: https://vietnamnews.vn/society/1036762/con-dao-to-return-to-new-normal-under-provinces-proposal.html

Continue Reading

Society

Five teens killed in road crash during Mid-Autumn Festival in northern Vietnam

Published

on

Five teenage boys were killed and two others injured following a road accident involving four motorbikes that were traveling at high speed in the northern Vietnamese province of Phu Tho on Tuesday night.

The crash took place along a street in Minh Tan Commune, Cam Khe District at around 10:30 pm, according to Nguyen Hong Son, chairman of the commune’s People’s Committee.

A total of seven teenagers were traveling on four motorbikes at high speed when they crashed into one another.

Four of them were killed on the spot, while the other three were admitted to the hospital with serious injuries.

One of the injured later died at around 1:00 am on Wednesday.

The five deceased victims were identified as Nguyen Ngoc Duy, 16, Nguyen Trung Dung, 16, Doan Quoc Hoi, 17, Nguyen Thanh Toan, 18, and Nguyen Truong Son, 16, according to An Toan Giao Thong (Traffic Safety) newspaper, which is managed by the National Committee for Traffic Safety.

Khuat Viet Hung, vice-chairman of the committee, has requested authorities in Phu Tho to promptly carry out an investigation and find out the cause of the accident.

Hung directed competent authorities to check whether the victims were under the influence of drugs or alcohol, and to verify any signs of illegal street racing.

The boys are believed to have been celebrating the Mid-Autumn Festival prior to the crash, the provincial traffic safety committee reported.

The National Committee for Traffic Safety also asked their family members to pay attention to pandemic prevention and control measures when organizing funerals for the victims.

Like us on Facebook or follow us on Twitter to get the latest news about Vietnam!

Source: https://tuoitrenews.vn/news/society/20210922/five-teens-killed-in-road-crash-during-midautumn-festival-in-northern-vietnam/63216.html

Continue Reading

Trending