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Việt Nam’s COVID vaccine developer stops third phase trial due to volunteers shortage

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COVIVAC vaccine is developed by the Health Ministry’s Institute of Vaccines and Medical Biologicals (IVAC). —VNA/ Photo 

HÀ NỘI — The third phase of clinical trials of Việt Nam’s homemade COVID-19 vaccine COVIVAC have been halted, due to a shortage of volunteers. 

The Institute of Vaccines and Medical Biologicals (IVAC) under the Ministry of Health said that they are struggling to find people to test the drugs because so many have already been vaccinated.

A representative from IVAC told online newspaper dantri.com.vn on Tuesday that the institute needs around 4,000 volunteers for the third phase to be conducted this month.

The representative said: “The coverage of the COVID-19 vaccine in Việt Nam is very high. Therefore, we have difficulty recruiting volunteers who have not received the COVID-19 vaccine and meet the other criteria of the study. Volunteers from the same community are preferred as we can’t recruit a few volunteers from different places.” 

This institute has been asked to seek out other options, including research on a booster vaccine dose for future use.

COVIVAC has been researched and developed by IVAC since May 2020. It is Việt Nam’s second COVID-19 vaccine, following Nanocovax to enter the clinical trial phase.

The COVIVAC vaccine is a Newcastle vector vaccine (NDV), which binds the protein S expression gene of the SARS-CoV-2 virus, and is produced using embryonic chicken egg technology. This technology is also used to produce seasonal flu vaccines circulating in Việt Nam.

According to the report, in phase one, COVIVAC vaccine was tested on 120 people, aged 18-59 years old, distributed into four test groups, 25 people each with vaccine doses of 1μg (microgram), 3μg, 10μg and 1μg + 1.5mg excipient CpG 1018, and the placebo group had 20 people injected with phosphate-buffered saline, pH=7.2.

As a result, all four vaccine dose groups had no adverse reactions to the vaccine. Regarding the immune response, all four different dose groups of COVIVAC vaccine had different levels of immune responses against SARS-CoV-2 neutralising antibodies and anti-S protein IgG antibodies. —

Source: https://vietnamnews.vn/society/1090227/viet-nams-covid-vaccine-developer-stops-third-phase-trial-due-to-volunteers-shortage.html

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Future is now

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The winners of the first VinFuture Prize have been revealed. Professors Kariko, Cullis and Weissman were awarded the Grand Prize of US$3 million for their research on mRNA vaccine technology.

Source: https://vietnamnews.vn/society/1118190/future-is-now.html

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15,935 new coronavirus cases recorded on Friday

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A student has his body temperature checked before entering class at Việt Đức High School in Hoàn Kiếm District of Hà Nội. — VNA/ Photo Thanh Tùng

HÀ NỘI — A total of 15,935 new COVID-19 patients were reported in Việt Nam on Friday, raising the total number to 2,110,737.

Thirty-four were imported infections and the remaining domestic. New cases were reported in 62 out of 63 provinces and cities across the country.

A total of 10,912 transmissions were detected in the community.

The capital city of Hà Nội again led the list, with 2,805 cases.

The other localities that reported new infections were Đà Nẵng (964), Hải Phòng (796), Hưng Yên (685), Bến Tre (618), Thanh Hóa (509), Quảng Ngãi (482), Bình Phước (475), Bình Định (420), Bắc Ninh (418), Quảng Ninh (369), Khánh Hòa (346), Quảng Nam (344), Hải Dương (341), Cà Mau (319), Bắc Giang (299), Vĩnh Phúc (280), Thừa Thiên Huế (280), Thái Nguyên (268), Vĩnh Long (263), Trà Vinh (240), Tây Ninh (237), Nghệ An (233), Lâm Đồng (231), HCM City (227), Nam Định (223), Phú Thọ (209), Hòa Bình (208), Thái Bình (187), Ninh Bình (151), Lào Cai (134), Tuyên Quang (129), Hà Nam (128), Bà Rịa – Vũng Tàu (127), Điện Biên (115), Bạc Liêu (113), Lạng Sơn (112), Đắk Nông (101), Gia Lai (99), Sơn La (99), Hà Giang (99), Bình Dương (95), Quảng Bình (90), Hậu Giang (87), Phú Yên (84), Yên Bái (84), Đồng Tháp (81), Kon Tum (73), Kiên Giang (72), Bình Thuận (71), Cần Thơ (61), Quảng Trị (56), Sóc Trăng (55), Hà Tĩnh (52), Đồng Nai (51), Cao Bằng (51), An Giang (39), Ninh Thuận (31), Tiền Giang (28), Long An (22), Lai Châu (22) and Bắc Kạn (13).

Việt Nam has seen 133 cases of the Omicron variant so far, in Hà Nội (12), Quảng Nam (27), HCM City (65), Hải Dương (1), Hải Phòng (1), Thanh Hóa (2), Đà Nẵng (8), Khánh Hòa (11), Long An (1) and Quảng Ninh (2).

A further 2,256 patients were declared recovered, taking the number of people given the all-clear so far to 1,797,180.

A total of 177 fatalities related to COVID-19 were announced. To date, the country has had 36,443 deaths, making up 1.7 per cent of total infections and ranking 25th out of 224 countries and territories worldwide.

More than 173.7 million doses of COVID-19 vaccines have been administered across the country so far. —

Source: https://vietnamnews.vn/society/1118156/15935-new-coronavirus-cases-recorded-on-friday.html

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Update of COVID-19 new cases in Việt Nam on Jan. 21 afternoon

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From 16:00 on January 20 to 16:00 on January 21, 15,935 new infections were recorded on the National COVID-19 Case Management System.
 
Provinces and cities with confirmed cases are as follows: Hà Nội (2,805), Đà Nẵng (964), Hải Phòng (796), Hưng Yên (685), Bến Tre (618), Thanh Hóa (509), Quảng Ngãi (482), Bình Phước (475), Bình Định (420), Bắc Ninh (418), Quảng Ninh (369), Khánh Hòa (346), Quảng Nam (344), Hải Dương (341), Cà Mau (319), Bắc Giang (299), Vĩnh Phúc (280), Thừa Thiên Huế (280), Thái Nguyên (268), Vĩnh Long (263), Trà Vinh (240), Tây Ninh (237), Nghệ An (233), Lâm Đồng (231), HCM City (227), Nam Định (223), Phú Thọ (209), Hòa Bình (208), Thái Bình (187), Ninh Bình (151), Lào Cai (134), Tuyên Quang (129), Hà Nam (128), Bà Rịa – Vũng Tàu (127), Điện Biên (115), Bạc Liêu (113), Lạng Sơn (112), Đắk Nông (101), Gia Lai (99), Sơn La (99), Hà Giang (99), Bình Dương (95), Quảng Bình (90), Hậu Giang (87), Phú Yên (84), Yên Bái (84), Đồng Tháp (81), Kon Tum (73), Kiên Giang (72), Bình Thuận (71), Cần Thơ (61), Quảng Trị (56), Sóc Trăng (55), Hà Tĩnh (52), Đồng Nai (51), Cao Bằng (51), An Giang (39), Ninh Thuận (31), Tiền Giang (28), Long An (22), Lai Châu (22), Bắc Kạn (13).
 
Up to now, Việt Nam has recorded 130 cases of COVID-19 due to Omicron variant in Hà Nội (12), Quảng Nam (27), HCM City (65), Hải Dương (1), Hải Phòng (1), Thanh Hóa (2), Đà Nẵng (8), Khánh Hòa (11), Long An (1), Quảng Ninh (2).

Source: https://vietnamnews.vn/society/1118126/update-of-covid-19-new-cases-in-viet-nam-on-jan-21-afternoon.html

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